Testicular Diseases
Testicular Infection
Cause: Concurrent infection of the testes and epididymus (orchiepididymitis)
may occur as a result of microorganisms including Staphylococcus,
Streptococcus, coliforms, Mycoplasma, Ureaplasma, or Brucella canis. Localized
wounds or spread of infectious organisms from distant sites in the body via the
circulatory or lymphatic systems may lead to testicular infection.
Additionally, infections of the urinary tract system or of the prostate gland
may spread to the testes/epididymus through the ductus deferens.
Symptoms: Infections associated with orchiepididymitis present with scrotal
swelling, testicular enlargement, pain, and fever.
Diagnosis: Ultrasound imaging of the testes will confirm
inflammation associated with infection and rule out other potential causes for
testicular swelling. Bacterial culture of the semen in Amies medium allows for
isolation of Ureaplasma, Mycoplasma, and aerobic bacteria. Ultrasound imaging
indicating that inflammation is localized primarily to the epididymides is
highly suspicious of Brucella canis infection. Accordingly, serological testing
for Brucella canis should be performed.
Treatment and Prognosis: Treatment of testicular infections
includes administration of antibiotics and anti-inflammatories. Castration is
recommended in males that are not intended to be used for breeding or in those
diagnosed with Brucella canis (since treatment of the latter fails to
completely eradicate infection and only reduces infection to a "carrier state").
In those males whose owners wish to salvage reproductive function, additional
treatment with cool compresses may help in reducing heat in the scrotum
associated with inflammation, and may assist in reducing permanent detrimental
effects on spermatogenesis. Chronic or treatment-resistant infections, however,
typically result in sterility due to destruction of the spermatogenetic tissue
by the inflammatory process. In those dogs in which infection is eradicated by
treatment, permanent side effects on spermatogenesis have been observed,
therefore, prognosis in regard to fertility is guarded.